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  Primary Pulmonary Extranodal Marginal Zone Lymphoma: An Atypical Radiological Pattern [Respir Case Rep]
Respir Case Rep. 2017; 6(3): 166-169 | DOI: 10.5505/respircase.2017.98698  

Primary Pulmonary Extranodal Marginal Zone Lymphoma: An Atypical Radiological Pattern

Pınar Akın Kabalak1, Miraç Öz1, Duygu Kankaya2, Aydın Çiledağ1, Çetin Atatsoy3, Muhit Özcan4, Özlem Özdemir Kumbasar1
1Department Of Chest Disease, Ankara University, Faculty of Medicine, Ankara, Turkey
2Department Of Pathology, Ankara University, Faculty of Medicine, Ankara, Turkey
3Department Of Radiology, Ankara University, Faculty of Medicine, Ankara, Turkey
4Department Of Hematology, Ankara University, Faculty of Medicine, Ankara, Turkey

Primary pulmonary extranodal marginal zone lymphoma (PPEMZL) arising from the mucosa-associated lymphoid tissue of the bronchus is a very rare disorder. It appears in the form of a slowly progressing localized mass or consolidation. Clinical presentation may include non-specific pulmonary symptoms, such as chronic cough, or dyspnea, but it is more often diagnosed incidentally. Computed tomography (CT) the thorax revealed that the present patient had a giant cystic lesion, parenchymal nodules, and consolidation area. The patient was symptomatic and diagnosed as marginal zone lymphoma by immunohistochemical study of the transthoracic biopsy specimen. This patient is thought to be the first diagnosed as PPEMZL from a cystic lesion.

Keywords: Cystic lesion, immunohistochemical staining, pulmonary lymphoma, marginal zone


Primer Pulmoner Ekstranodal Marjinal Zon Lenfoma: Atipik Radyolojik Görünüm

Pınar Akın Kabalak1, Miraç Öz1, Duygu Kankaya2, Aydın Çiledağ1, Çetin Atatsoy3, Muhit Özcan4, Özlem Özdemir Kumbasar1
1Ankara Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Ana Bilim Dalı, Ankara
2Ankara Üniversitesi Tıp Fakültesi, Patoloji Ana Bilim Dalı, Ankara
3Ankara Üniversitesi Tıp Fakültesi, Radyoloji Ana Bilim Dalı, Ankara
4Ankara Üniversitesi Tıp Fakültesi, Hematoloji Ana Bilim Dalı, Ankara

Bronşa ait mukoza ilişkili lenfoid dokudan kaynaklanan primer pulmoner ekstranodal marjinal zon lenfoma nadir görülmektedir. Yavaş progrese olan lokalize kitle ya da konsolidasyon olarak ortaya çıkar. Kronik öksürük, dispne gibi non-spesifik pulmoner semptomlar olabilir ama sıklıkla tesadüfen tanı alır. Hastamıza ait toraks tomografisinde dev kistik bir lezyon ve eşlik eden konsolidasyon ve nodüller vardı. Transtorasik akciğer biopsisi ve immünhistokimayasal inceleme ile marjinal zon lenfoma tanısı elde edildi. Dev kistik lezyon ile radyolojik bulgu veren ilk olgu olarak sunmayı amaçladık.

Anahtar Kelimeler: Kistik lezyon, immünhistokimyasal boyama, pulmoner lenfoma, marjinal zon


Tomography Slices of the Case




Pınar Akın Kabalak, Miraç Öz, Duygu Kankaya, Aydın Çiledağ, Çetin Atatsoy, Muhit Özcan, Özlem Özdemir Kumbasar. Primary Pulmonary Extranodal Marginal Zone Lymphoma: An Atypical Radiological Pattern. Respir Case Rep. 2017; 6(3): 166-169

Corresponding Author: Pınar Akın Kabalak, Türkiye


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