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Laparoscopic Endoscopic Surgical Science Dapson Kullanmna Bal Gelien Methemoglobinemi: Olgu Sunumu [Respir Case Rep]
Respir Case Rep. 2021; 10(3): 198-201 | DOI: 10.5505/respircase.2021.61224

Dapson Kullanmna Bal Gelien Methemoglobinemi: Olgu Sunumu

Recai Ergn, Serap Atik, Dilek Ergn, Fikret Kanat
Seluk niversitesi Seluklu Tp Fakltesi, Gs Hastalklar Anabilim Dal, Konya

Dapson genellikle iyi tolere edilmesine ramen hematolojik yan etkiler gsterebilmektedir. Methemoglobinemi ender grlen bir klinik durum olmasna karn, zamannda ve uygun tedavi edilmedii takdirde lme neden olabilir. Yirmi bir yanda erkek hasta nefes darl nedeni ile polikliniimize bavurdu. Oda havasnda llen okijen saturasyonu %88 idi. yk, fizik muayene ve tetkiklerinde nefes darln aklayacak bulgu yoktu. Arter kan gaznda methemoglobin dzeyi yksek (Fmethb: 10,6) olarak saptand. Dispne ve hipoksi bulgular olan hastada ayrntl anamnezde IG A Dermatitine bal dapson kullanm olduu renildi. IG A dermatiti nedeniyle dapson kullanan ve dispne ile bavuran gen hastada hipoksemi ve methemoglobineminin nadir nedenlerinden olan dapson kullanmn akla getirmek adna bu olguyu sunuyoruz.

Anahtar Kelimeler: Methemoglobinemi, dapson, hipoksemi.

Methemoglobulinemia due to Dapson Use: A Case Report

Recai Ergn, Serap Atik, Dilek Ergn, Fikret Kanat
Department of Chest Diseases, Seluk University Faculty of Medicine, Konya, Turkey

Dapson, although generally well tolerated, can lead to hematological side effects. Although methemoglobinemia is a rare clinical condition, it can culminate in death if not treated in a timely and appropriate manner. A 21-year-old male patient presented to our outpatient clinic with shortness of breath, with oxygen saturation in ambient air measured by pulse oximetry at 88%. His initial medical history and physical examination were unremarkable for possible causes of dyspnea, while arterial blood gas measurements revealed methemoglobin elevation (Fmethb: 10.6). Detailed history revealed that dyspnea with subsequent hypoxia had started after dapsone treatment due to IgA dermatitis. We present this case report to highlight the possible role of dapsone as a rare cause of hypoxemia and methemoglobinemia, as exemplified in this young patient undergoing dapsone treatment for IgA dermatitis in which dyspnea was the initial symptom.

Keywords: Methemoglobinemia, dapson, hypoxemia.

Recai Ergn, Serap Atik, Dilek Ergn, Fikret Kanat. Methemoglobulinemia due to Dapson Use: A Case Report. Respir Case Rep. 2021; 10(3): 198-201

Sorumlu Yazar: Recai Ergn, Trkiye
Makale Dili: ngilizce
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