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Laparoscopic Endoscopic Surgical Science Aripiprazol Kullanmna Bal Nadir Grlen nterstisyel Pnmoni: Olgu Sunumu [Respir Case Rep]
Respir Case Rep. 2022; 11(1): 44-49 | DOI: 10.5505/respircase.2022.80948

Aripiprazol Kullanmna Bal Nadir Grlen nterstisyel Pnmoni: Olgu Sunumu

Glistan Alpagat, Aye Baccolu, Smeyra Alan Yalm, Merve Poyraz, Betl Dumanou, Aye Fsun Kalpaklolu
Krkkale niversitesi Tp Fakltesi, mmunoloji ve Allerji Hastalklar, Krkkale

nterstisyel akcier hastalklarnn (IAH) %2-3'unun ilalara bal olduu ve ilaca bal akcier hastalklarnn %70'inin IAH'dan olduu kabul edilmektedir. Elli bir yanda kadn hasta 3 yldr bipolar bozukluk iin aripiprazol kullanmakta ve 2 yldr astm tedavisi grmekteydi. Hastann klinii, solunum fonksiyon testinde (SFT) restriktif patern olmas, azalm karbon monoksit difzyon testi, laboratuvar sonular, radyolojik bulgular ve biyopsi ile IAH dnld. Olas etiyolojiler: enfeksiyon, aspirasyon, kalp yetmezlii, evcil hayvan besleme durumu, tehlikeli solunum maddelerine maruziyet dland. pheli ila kesilerek, oral kortikosteroid tedavisi baland. la tedavileri ile akcier toksisitesi geliebilir. la yks ayrntl olarak sorgulanmal ve phe durumunda derhal kesilmelidir. IAH nadir grlr; ilatan phelenilmez de devam edilirse hastalk kronikleebilir ve solunum yetmezliine ilerleyebilir. Hastalkla ilgili farkndal artrmak iin bu olguyu sunmaya amaladk.

Anahtar Kelimeler: nterstisyel Akcier Hastal, aripiprazol, interstisyel pnmoni, steroid tedavi

Rare Interstitial Pneumonia Due to the Use of Aripiprazol: A Case Report

Glistan Alpagat, Aye Baccolu, Smeyra Alan Yalm, Merve Poyraz, Betl Dumanou, Aye Fsun Kalpaklolu
Department of Immunology and Allergy Disease, Krkkale University Faculty of Medicine, Krkkale, Turkey

It is accepted that 23% of interstitial lung diseases (ILD) are due to drugs, and that 70% of drug-induced lung diseases are due to ILD. We present here the case of a 51-year-old female patient who had been taking aripiprazole for bipolar disorder for 3 years and had been undergoing asthma treatment for 2 years. ILD was considered based on the patient's clinic, a restrictive pattern in the pulmonary function test (PFT), a decreased carbon monoxide diffusion test, laboratory results, radiological findings and biopsy. The possible etiologies of infection, aspiration, heart failure, pet feeding status and exposure to hazardous respiratory substances were excluded. The suspected drug was discontinued and oral corticosteroid treatment was started. Lung toxicity can develop with drug treatments, and so drug history should be questioned in detail and discontinued immediately in case of any doubt. ILD is rare, and if the drug is not suspected and continued, the disease may become chronic and progress to respiratory failure. We present this case to increase awareness of the disease.

Keywords: Interstitial Lung Disease, aripiprazole, interstitial pneumonitis, steroid treatment

Olgunun Grnt Kesitleri




Glistan Alpagat, Aye Baccolu, Smeyra Alan Yalm, Merve Poyraz, Betl Dumanou, Aye Fsun Kalpaklolu. Rare Interstitial Pneumonia Due to the Use of Aripiprazol: A Case Report. Respir Case Rep. 2022; 11(1): 44-49

Sorumlu Yazar: Glistan Alpagat, Trkiye
Makale Dili: ngilizce
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