Respir Case Rep. 2025; 14(2): 43-46 | DOI: 10.5505/respircase.2025.92678

Microscopic Polyangiitis Presenting with Uncommon Reversed Halo Sign: A Case Report

Shengquan Wei, Huixia Wang, Gen Li, Tiantian Lv, Ruzhen Jia
Department of Respiratory Medicine, Baoji People's Hospital, the Fifth Clinical Medical College of Yan'an University, Baoji City, China

This case report presents an uncommon manifestation of microscopic polyangiitis (MPA) characterized by an initial reversed halo sign (RHS) on chest computed tomography (CT). A 49-year-old female patient with a history of sensorineural hearing loss presented with progressive respiratory symptoms. Comprehensive clinical investigations, including chest CT, laboratory tests and renal biopsy, confirmed a diagnosis of MPA, and targeted treatment with glucocorticoids and cyclophosphamide resulted in significant improvement in the lung lesions. This report aims to increase clinical awareness of atypical presentations of MPA and to reduce potential diagnostic challenges.

Keywords: Microscopic polyangiitis, Reverse halo sign, tomography

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Nadir Görülen Ters Halo Ýþareti ile Ortaya Çýkan Mikroskopik Polianjitis: Olgu Sunumu

Shengquan Wei, Huixia Wang, Gen Li, Tiantian Lv, Ruzhen Jia
Baoji Halk Hastanesi, Yan'an Üniversitesi Beþinci Klinik Týp Fakültesi, Göðüs Hastalýklarý Anabilim Dalý, Baoji Þehri, Çin

Bu olgu sunumu, akciðer bilgisayarlý tomografisinde ilk olarak ters halo belirisi ile özdeþleþen, mikroskopik poliyanjitis (MPA)'nin nadir bir manifestasyonunu sunmaktadýr. Sensorineural iþitme kaybý geçmiþi olan 49 yaþýndaki bir kadýn hasta, ilerleyici solunum sistemi semptomlarý nedeniyle kabul edildi. Akciðer tomografisi, laboratuvar testleri ve böbrek biopsisi dahil kapsamlý klinik tetkikler, MPA tanýsýný doðruladý. Glukokortikoidler ve siklofosfamid ile hedeflenmiþ tedavi, akciðer lezyonlarýndaki önemli bir iyileþmeye neden oldu. Bu yazý, klinisyenlerin MPA'nýn atipik sunumuna olan duyarlýlýðýný arttýrmak ve potansiyel taný zorluklarýný azaltmak amacýyla hazýrlanmýþtýr.

Anahtar Kelimeler: Mikroskopik poliyanjitis, Ters halo belirisi, tomografi

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