e-ISSN 2147-2475
Cilt : 11 Say : 3 Yl : 2023

Hzl Arama




Laparoscopic Endoscopic Surgical Science Posterior Mediastenin Nadir Bir Tmr: yi Diferansiye Liposarkom [Respir Case Rep]
Respir Case Rep. 2022; 11(3): 170-175 | DOI: 10.5505/respircase.2022.24650

Posterior Mediastenin Nadir Bir Tmr: yi Diferansiye Liposarkom

Gzde Kalbaran Ksmet1, Oguzhan Okutan1, Seda Mazmanolu Atlman2, Ismail Ylmaz3
1SB Sultan 2. Abdlhamid Han SUAM, Gs Hastalklar Servisi, stanbul
2Haydarpaa Numune Eitim ve Aratrma Hastanesi, Patoloji Servisi, stanbul
3SB Sultan 2. Abdlhamid Han SUAM, Patoloji Servisi, stanbul

Liposarkom erikinlerde en sk grlen yumuak doku sarkomlarndan biridir; genellikle alt ekstremitelerde ve retroperitonda ortaya kar. Miksoid, iyi diferansiye, farkllamam (dediferansiye) ve pleomorfik olmak zere eitli histolojik alt tipleri vardr. Mediastenden kaynaklanan liposarkomlar son derece nadirdir. Bu tmrler genellikle yava byrler ve asemptomatik kalrlar ancak byk boyuta ulap komu yaplara bas yaptnda semptomatik olabilirler. Bilgisayarl tomografi ve manyetik rezonans grntleme tan iin faydal veriler salar. Kesin tan iin doku biyopsisi gereklidir ve tans tipik patolojik zelliklere dayanr. Kemoradyoterapiye duyarl olmadndan tam cerrahi rezeksiyon birinci basamak tedavi seeneidir. Nks oran yksek olduundan uzun sreli takip yaplmaldr. Bu yazda ksrk ikayeti ile bavuran primer mediastinal liposarkomlu 56 yanda kadn olgu nadir grlmesi sebebiyle sunuldu.

Anahtar Kelimeler: Atipik Lipomatz Tmr, CDK4, yi Diferansiye Liposarkom, MDM2

A Rare Tumor of the Posterior Mediastinum: Well-Differentiated Liposarcoma

Gzde Kalbaran Ksmet1, Oguzhan Okutan1, Seda Mazmanolu Atlman2, Ismail Ylmaz3
1Department of Chest Diseases, University of Health Sciences Trki-ye, Hamidiye Faculty of Medicine, Sultan 2. Abdlhamid Han Health Application and Research Center, stanbul, Trkiye
2Department of Pathology, Haydarpaa Numune Training and Re-search Hospital, stanbul, Trkiye
3Department of Pathology, University of Health Sciences Trkiye, Hamidiye Faculty of Medicine, Sultan II. Abdlhamid Han Health Application and Research Center, stanbul, Trkiye

Liposarcoma is one of the most common forms of soft tissue sarcoma in adults, and usually occurs in the lower extremities and retroperitoneum. It has several histological subtypes, including myxoid, well-differentiated, dedifferentiated and pleomorphic. Liposarcomas originating from the mediastinum are extremely rare, and usually grow slowly and remain asymptomatic, but may become symptomatic when they become large enough to press on the adjacent structures. Computed tomography and magnetic resonance imaging provide useful data for diagnosis, while tissue biopsy based on typical pathological features is required for a definitive diagnosis. Complete surgical resection is the first-line treatment option as it is resistant to chemoradiotherapy. Due to the high risk of recurrence, long-term follow-up should be continued. We present here the rare case of a 56-year-old female patient with primary mediastinal liposarcoma who presented with a complaint of cough.

Keywords: Atypical Lipomatous Tumor, CDK4, Well-Differentiated Liposarcoma, MDM2

Olgunun Grnt Kesitleri




Gzde Kalbaran Ksmet, Oguzhan Okutan, Seda Mazmanolu Atlman, Ismail Ylmaz. A Rare Tumor of the Posterior Mediastinum: Well-Differentiated Liposarcoma. Respir Case Rep. 2022; 11(3): 170-175

Sorumlu Yazar: Gzde Kalbaran Ksmet, Trkiye
Makale Dili: ngilizce
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