D�k�m Duman�na ve U�ucu Organik Bile�iklere Maruz Kal�m ile �li�kili Olabilecek Pulmoner Kapiller Hemanjiomatozis Olgusu

Coskun Beyan, Ayse; Cimrin, Arif; G�rel, Duygu

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D�k�m Duman�na ve U�ucu Organik Bile�iklere Maruz Kal�m ile �li�kili Olabilecek Pulmoner Kapiller Hemanjiomatozis Olgusu [Respir Case Rep]

Respir Case Rep. 2020; 9(3): 108-111 | DOI: 10.5505/respircase.2020.70894

D�k�m Duman�na ve U�ucu Organik Bile�iklere Maruz Kal�m ile �li�kili Olabilecek Pulmoner Kapiller Hemanjiomatozis Olgusu

Ayse Coskun Beyan¹, Arif Cimrin¹, Duygu G�rel²
¹Dokuz Eyl�l �niversitesi, �� ve Meslek Hastal�klar� Bilim Dal�, �zmir
²Dokuz Eyl�l �niversitesi, Patoloji Ana Bilim Dal�, �zmir

Pulmoner kapiller hemanjiomatozis (PKH) nadir g�r�len, ilerleyici ve �o�unlukla pulmoner hipertansiyon ile birlikte bulunan akci�erlerin vask�ler bir hastal��d�r. Hastal�kla ili�kili mesleksel risk fakt�rleri ile ilgili ara�t�rma azd�r. Ayn� i�letmeden ba�vuran 8 olgunun 3 ��nde benzer radyolojik bulgulara rastland�, olgular�n yaln�zca bir tanesi akci�er biopsisini kabul etti. K�rk ya��nda erkek olgunun herhangi bir yak�nmas� yoktu. Bilgisayarl� tomografide her iki akci�erde orta derecede peribron�iyal kal�nla�ma ve alt b�lgelerde mozaik perf�zyon paterni izlendi. Kardiyak de�erlendirmede sa� kalp yetmezli�i saptanmad�. Akci�er biopsisinde alveolar septada kapiller benzeri vask�ler proliferasyon g�r�n�m� izlendi. Ayn� i�letmeden benzer 3 radyolojik bulgu olmas� ve literat�r bulgular� e�li�inde mesleksel maruz kal�m ile ili�kili PKH olgusu olabilece�i d��n�ld�. PKH etiyolojisi halen bilinmeyen bir hastal�kt�r. Mesleki maruziyetler PKH i�in potansiyel bir risk fakt�r� olarak bildirilmektedir. Herhangi bir hastal�k i�in bilinen klasik epidemiyolojik �zelliklerin kar��lanmad�� durumlarda mesleki etiyolojinin de�erlendirilmesi unutulmamal�d�r.

Anahtar Kelimeler: D�k�m, meslek hastal��, d�k�m duman�, u�ucu organik bile�ikler

A Case of Pulmonary Capillary Hemangiomatosis in a Worker with Exposure to Foundry Dust and VOCs

Ayse Coskun Beyan¹, Arif Cimrin¹, Duygu G�rel²
¹Dokuz Eylul University, Occupational Medicine Department, �zmir
²Dokuz Eylul University, Pathology Department, �zmir

Pulmonary capillary hemangiomatosis (PCH) is a rare and progressive vascular disease of the lung that causes pulmonary hypertension, as they frequently overlap. The occupational risk factor associated with PCH is rarely discussed. In the present report, three of the eight patients admitted from the same company had similar radiological findings, and one agreed to undergo a biopsy. A 40-year-old male who was working as a foundry worker with no symptoms underwent CT, which showed moderate peribronchial thickening in both lungs and a mosaic perfusion pattern in the lower zones. There was no evidence of right heart failure. A microscopic examination of the lung by thoracoscopic resection showed capillary-like vascular proliferation in the alveolar septa. As there were workers with similar radiological findings from the same company he was diagnosed with occupational PCH. The etiology of PCH remains unknown. Occupational exposure should be kept in mind if a disease does not meet the classic epidemiological characteristics.

Keywords: Foundry, Occupational disease, foundry dust, VOC

Ayse Coskun Beyan, Arif Cimrin, Duygu G�rel. A Case of Pulmonary Capillary Hemangiomatosis in a Worker with Exposure to Foundry Dust and VOCs. Respir Case Rep. 2020; 9(3): 108-111

Sorumlu Yazar: Ayse Coskun Beyan, T�rkiye

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