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Laparoscopic Endoscopic Surgical Science Aklda Tut: Klomifen Sitrat Kullanmna Bal Pulmoner Emboli [Respir Case Rep]
Respir Case Rep. 2021; 10(2): 126-129 | DOI: 10.5505/respircase.2021.18291

Aklda Tut: Klomifen Sitrat Kullanmna Bal Pulmoner Emboli

Buket Mermit ilingir, Hanifi Yldz, Aysel Sunnetcioglu
Van Yznc Yl niversitesi Tp Fakltesi, Gs Hastalklar Anabilim Dal, Van

Yirmi sekiz yandaki bayan hasta bir gndr devam eden gs ars nedeniyle bavurdu. Ovulatuar disfonksiyonun klomifen sitrat ile tedavisi 20 gn nce balatlmt. Hastann nabz hz 120 vuru / dakika ve kan basnc 100/60 mmHg idi. Elektrokardiyografide sins taikardisi saptand. Arteriyel kan gaz testi sonucunda hem hipoksi hem de hipokapni tespit edildi. D-dimer seviyesi 5.2 g / ml olarak lld. Bilgisayarl tomografi anjiyografisinde sa alt lob pulmoner arter ve alt lob segment dallarnda pulmoner emboli ile uyumlu dolum defektleri grld. Transtorasik ekokardiyografide ejeksiyon fraksiyonu% 65 idi ve trombs izlenmedi. Hastaya klomifen sitrat kullanmna bal pulmoner emboli tans kondu. Bemiparin sodyum ile antikoaglan tedavi baland ve hasta taburcu edildi. Klomifen sitrat kullanmna bal akut pulmoner emboli, nadir grlen ancak karlaldnda yaam tehdit eden bir komplikasyon olabilir. Doktorlar olas pulmoner emboli riskinin farknda olmaldr.

Anahtar Kelimeler: Pulmoner emboli, klomifen sitrat, infertilite.

Keep in Mind: Pulmonary Embolism Due to the Use of Clomiphene Citrate

Buket Mermit ilingir, Hanifi Yldz, Aysel Sunnetcioglu
Department of Chest Diseases, Van Yznc Yl University Faculty of Medicine, Van, Turkey

A 28-year-old female patient was admitted with ongoing chest pain for one day, having started treatment for ovulatory dysfunction with clomiphene citrate 20 days prior. The patient's pulse rate was 120 bpm and blood pressure was 100/60 mmHg. Sinus tachycardia was detected on electrocardiography. Both hypoxia and hypocapnia were detected on an arterial blood gas test. The patients d-dimer level was measured as 5.2 g/ml. A computed tomography angiography revealed filling defects in the right lower lobe pulmonary artery and lower lobe segment branches, consistent with pulmonary embolism. The ejection fraction was 65% on the transthoracic echocardiography and no thrombus was observed. The patient was diagnosed with pulmonary embolism due to clomiphene citrate use, and started on anticoagulation therapy with bemiparin sodium, and was subsequently discharged. Acute pulmonary embolism due to the use of clomiphene citrate is an uncommon but life-threatening complication when encountered. Physicians should be aware of the potential risk of pulmonary embolism.

Keywords: Pulmonary embolism, clomiphene citrate, infertility.

Buket Mermit ilingir, Hanifi Yldz, Aysel Sunnetcioglu. Keep in Mind: Pulmonary Embolism Due to the Use of Clomiphene Citrate. Respir Case Rep. 2021; 10(2): 126-129

Sorumlu Yazar: Buket Mermit ilingir, Trkiye
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